Insulin Pumping Patches: Emerging Insulin Delivery Systems
نویسندگان
چکیده
منابع مشابه
Glucose-responsive insulin delivery systems.
La diabetes es un trastorno de muy alta prevalencia, caracterizado por un déficit de acción insulínica, que da lugar a concentraciones elevadas de glucosa en sangre. Las terapias sustitutivas son muy imperfectas: en pocos casos consiguen controlar de manera estable los valores de glucemia, se adaptan mal a las perturbaciones (ingestas, ejercicio, etc.), provocan hipoglucemias e implican un esfu...
متن کاملEvaluation of an Ultrasonic Insulin Delivery System in Hyperglycemic Rabbits
Introduction: Sonophoresis has been assessed as a novel approach to create skin permeability and drug delivery using low frequencies of ultrasound waves in the range of 20 kHz to 3 MHz. In this study, a system including seven 40 kHz piezoelectric transducers and an insulin chamber designed by the Medical Physics Research Center has been evaluated on hyperglycemic rabbits. Materials and Methods:...
متن کاملMicroneedle-array patches loaded with hypoxia-sensitive vesicles provide fast glucose-responsive insulin delivery.
A glucose-responsive "closed-loop" insulin delivery system mimicking the function of pancreatic cells has tremendous potential to improve quality of life and health in diabetics. Here, we report a novel glucose-responsive insulin delivery device using a painless microneedle-array patch ("smart insulin patch") containing glucose-responsive vesicles (GRVs; with an average diameter of 118 nm), whi...
متن کاملMicroneedle-array patches loaded with hypoxia-sensitive vesicles provide fast glucose-responsive insulin delivery
Joint Department of Biomedical Engineering, University of North Carolina at Chapel Hill and North Carolina State University, Raleigh, NC 27695; Molecular Pharmaceutics Division and Center for Nanotechnology in Drug Delivery, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599; and Department of Medicine, University of North Carolina School of Medicine...
متن کاملChanges in Altitude Cause Unintended Insulin Delivery From Insulin Pumps
OBJECTIVE Children and adults with type 1 diabetes who receive insulin pump therapy have reported hypoglycemia during air travel. We studied the effects of atmospheric pressure on insulin pump delivery. RESEARCH DESIGN AND METHODS Ten insulin pumps were connected to capillary tubes. The effects of changes in ambient pressure on insulin delivery, bubble formation, bubble size, and cartridge pl...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Diabetes Science and Technology
سال: 2018
ISSN: 1932-2968,1932-2968
DOI: 10.1177/1932296818814541